diff --git a/gui/wxpython/datacatalog/tree.py b/gui/wxpython/datacatalog/tree.py
index 2a3e8ed4fba..5f19af81cd7 100644
--- a/gui/wxpython/datacatalog/tree.py
+++ b/gui/wxpython/datacatalog/tree.py
@@ -23,6 +23,7 @@
 import re
 import copy
 from multiprocessing import Process, Queue, cpu_count
+from pathlib import Path
 
 import wx
 
@@ -354,7 +355,7 @@ def _getValidSavedGrassDBs(self):
         dbs = UserSettings.Get(
             group="datacatalog", key="grassdbs", subkey="listAsString"
         )
-        return [db for db in dbs.split(",") if os.path.isdir(db)]
+        return [db for db in dbs.split(",") if Path(db).is_dir()]
 
     def _saveGrassDBs(self):
         """Save current grass dbs in tree to settings"""
diff --git a/gui/wxpython/image2target/ii2t_gis_set.py b/gui/wxpython/image2target/ii2t_gis_set.py
index be7f6a46345..d31d9eaa48e 100644
--- a/gui/wxpython/image2target/ii2t_gis_set.py
+++ b/gui/wxpython/image2target/ii2t_gis_set.py
@@ -313,7 +313,7 @@ def _set_properties(self, version, revision):
         # set database
         if not self.gisdbase:
             # sets an initial path for gisdbase if nothing in GISRC
-            if os.path.isdir(os.getenv("HOME")):
+            if Path(os.getenv("HOME")).is_dir():
                 self.gisdbase = os.getenv("HOME")
             else:
                 self.gisdbase = str(Path.cwd())
@@ -331,7 +331,7 @@ def _set_properties(self, version, revision):
         location = self.GetRCValue("LOCATION_NAME")
         if location == "<UNKNOWN>":
             return
-        if not os.path.isdir(os.path.join(self.gisdbase, location)):
+        if not Path(os.path.join(self.gisdbase, location)).is_dir():
             location = None
 
         # list of locations
diff --git a/gui/wxpython/image2target/ii2t_manager.py b/gui/wxpython/image2target/ii2t_manager.py
index b2dd81c9ef3..0999cd26bf5 100644
--- a/gui/wxpython/image2target/ii2t_manager.py
+++ b/gui/wxpython/image2target/ii2t_manager.py
@@ -489,7 +489,7 @@ def OnLocation(self, event):
         self.mapsetList = []
         for item in tmplist:
             if (
-                os.path.isdir(os.path.join(self.grassdatabase, self.xylocation, item))
+                Path(self.grassdatabase, self.xylocation, item).is_dir()
                 and Path(self.grassdatabase, self.xylocation, item, "WIND").exists()
             ):
                 if item != "PERMANENT":
diff --git a/gui/wxpython/lmgr/workspace.py b/gui/wxpython/lmgr/workspace.py
index 7f4d2bcc7c4..2d46d0d0943 100644
--- a/gui/wxpython/lmgr/workspace.py
+++ b/gui/wxpython/lmgr/workspace.py
@@ -208,7 +208,7 @@ def Load(self, filename):
                 self.lmgr.SetSize(gxwXml.layerManager["size"])
             if gxwXml.layerManager["cwd"]:
                 self.lmgr.cwdPath = gxwXml.layerManager["cwd"]
-                if os.path.isdir(self.lmgr.cwdPath):
+                if Path(self.lmgr.cwdPath).is_dir():
                     os.chdir(self.lmgr.cwdPath)
 
         #
diff --git a/lib/init/grass.py b/lib/init/grass.py
index 0c67498c447..564ef8fb939 100755
--- a/lib/init/grass.py
+++ b/lib/init/grass.py
@@ -381,12 +381,12 @@ def create_grass_config_dir() -> str:
     except (RuntimeError, NotADirectoryError) as e:
         fatal(f"{e}")
 
-    if not os.path.isdir(directory):
+    if not Path(directory).is_dir():
         try:
             Path(directory).mkdir(parents=True)
         except OSError as e:
             # Can happen as a race condition
-            if e.errno != errno.EEXIST or not os.path.isdir(directory):
+            if e.errno != errno.EEXIST or not Path(directory).is_dir():
                 fatal(
                     _(
                         "Failed to create configuration directory '{}' with error: {}"
@@ -700,7 +700,7 @@ def cannot_create_location_reason(gisdbase: StrPath, location: str) -> str:
         return _(
             "Unable to create new project <{location}> because <{path}> is a file."
         ).format(**locals())
-    if os.path.isdir(path):
+    if Path(path).is_dir():
         return _(
             "Unable to create new project <{location}> because"
             " the directory <{path}>"
@@ -851,7 +851,7 @@ def set_mapset(
                             " because <{path}> is a file."
                         ).format(mapset=mapset, path=path)
                     )
-                elif os.path.isdir(path):
+                elif Path(path).is_dir():
                     # not a valid mapset, but dir exists, assuming
                     # broken/incomplete mapset
                     warning(
@@ -2181,7 +2181,7 @@ def main() -> None:
     GRASS_VERSION_MAJOR = runtime_paths.version_major
     GRASS_VERSION_GIT = runtime_paths.grass_version_git
     gisbase = runtime_paths.gisbase
-    if not os.path.isdir(gisbase):
+    if not Path(gisbase).is_dir():
         gisbase = get_install_path(gisbase)
         # Set the main prefix again.
         # See also grass.script.setup.setup_runtime_env.
diff --git a/pyproject.toml b/pyproject.toml
index 609c86d9002..0dbc7549763 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -214,7 +214,6 @@ ignore = [
     "PTH107",  # os-remove
     "PTH108",  # os-unlink
     "PTH111",  # os-path-expanduser
-    "PTH112",  # os-path-isdir
     "PTH117",  # os-path-isabs
     "PTH118",  # os-path-join
     "PTH119",  # os-path-basename
diff --git a/python/grass/app/runtime.py b/python/grass/app/runtime.py
index 2f72088a1e9..24ce4c060d0 100644
--- a/python/grass/app/runtime.py
+++ b/python/grass/app/runtime.py
@@ -157,7 +157,7 @@ def get_grass_config_dir_for_version(major_version, minor_version, *, env):
         )
         raise RuntimeError(msg)
 
-    if not os.path.isdir(config_dir):
+    if not Path(config_dir).is_dir():
         msg = (
             f"The {env_dirname} variable points to directory which does"
             " not exist, ask your operating system support"
diff --git a/python/grass/app/tests/grass_app_resource_paths_test.py b/python/grass/app/tests/grass_app_resource_paths_test.py
index 6cd5dde7c73..c6d9299c83b 100644
--- a/python/grass/app/tests/grass_app_resource_paths_test.py
+++ b/python/grass/app/tests/grass_app_resource_paths_test.py
@@ -1,4 +1,3 @@
-import os
 from pathlib import Path
 
 import pytest
@@ -39,4 +38,4 @@ def test_value_not_empty(name):
 def test_value_is_directory(name):
     value = getattr(resource_paths, name)
     assert Path(value).exists()
-    assert os.path.isdir(value)
+    assert Path(value).is_dir()
diff --git a/python/grass/pygrass/gis/__init__.py b/python/grass/pygrass/gis/__init__.py
index e9f7469a4fe..efc09af359f 100644
--- a/python/grass/pygrass/gis/__init__.py
+++ b/python/grass/pygrass/gis/__init__.py
@@ -1,10 +1,11 @@
 #!/usr/bin/env python3
 
 from os import listdir
-from os.path import join, isdir
+from os.path import join
 import shutil
 import ctypes as ct
 import fnmatch
+from pathlib import Path
 
 
 import grass.lib.gis as libgis
@@ -243,7 +244,7 @@ def __iter__(self):
         return (
             m
             for m in listdir(lpath)
-            if (isdir(join(lpath, m)) and is_valid(m, lpath, "MAPSET"))
+            if (Path(lpath, m).is_dir() and is_valid(m, lpath, "MAPSET"))
         )
 
     def __len__(self):
diff --git a/python/grass/pygrass/modules/grid/grid.py b/python/grass/pygrass/modules/grid/grid.py
index d80790cfca8..a177fd76c83 100644
--- a/python/grass/pygrass/modules/grid/grid.py
+++ b/python/grass/pygrass/modules/grid/grid.py
@@ -139,7 +139,7 @@ def get_mapset(gisrc_src, gisrc_dst):
     mdst, ldst, gdst = read_gisrc(gisrc_dst)
     path_src = os.path.join(gsrc, lsrc, msrc)
     path_dst = os.path.join(gdst, ldst, mdst)
-    if not os.path.isdir(path_dst):
+    if not Path(path_dst).is_dir():
         Path(path_dst).mkdir(parents=True)
         copy_special_mapset_files(path_src, path_dst)
     src = Mapset(msrc, lsrc, gsrc)
@@ -273,7 +273,7 @@ def copy_rasters(rasters, gisrc_src, gisrc_dst, processes, region=None):
         # change gisdbase to dst
         env["GISRC"] = gisrc_dst
         rupck(input=file_dst, output=rast_clean, overwrite=True, env_=env)
-        os.remove(file_dst)
+        Path(file_dst).unlink()
 
 
 def copy_vectors(vectors, gisrc_src, gisrc_dst):
@@ -307,7 +307,7 @@ def copy_vectors(vectors, gisrc_src, gisrc_dst):
         # change gisdbase to dst
         env["GISRC"] = gisrc_dst
         vupck(input=file_dst, output=vect, overwrite=True, env_=env)
-        os.remove(file_dst)
+        Path(file_dst).unlink()
 
 
 def get_cmd(cmdd):
@@ -395,7 +395,7 @@ def cmd_exe(args):
     # run the grass command
     sub.Popen(get_cmd(cmd), shell=shell, env=env).wait()
     # remove temp GISRC
-    os.remove(gisrc_dst)
+    Path(gisrc_dst).unlink()
 
 
 class GridModule:
@@ -539,7 +539,7 @@ def __init__(
     def __del__(self):
         if self.gisrc_dst:
             # remove GISRC file
-            os.remove(self.gisrc_dst)
+            Path(self.gisrc_dst).unlink()
 
     def clean_location(self, location=None):
         """Remove all created mapsets.
@@ -730,7 +730,7 @@ def _clean(self):
             gisdbase, location = os.path.split(self.move)
             self.clean_location(Location(location, gisdbase))
             # rm temporary gis_rc
-            os.remove(self.gisrc_dst)
+            Path(self.gisrc_dst).unlink()
             self.gisrc_dst = None
             sht.rmtree(os.path.join(self.move, "PERMANENT"))
             sht.rmtree(os.path.join(self.move, self.mset.name))
diff --git a/python/grass/pygrass/utils.py b/python/grass/pygrass/utils.py
index 9a040a961dd..344e4237ea4 100644
--- a/python/grass/pygrass/utils.py
+++ b/python/grass/pygrass/utils.py
@@ -1,6 +1,7 @@
 import fnmatch
 import itertools
 import os
+from pathlib import Path
 from sqlite3 import OperationalError
 
 import grass.lib.gis as libgis
@@ -39,7 +40,7 @@ def findfiles(dirpath, match=None):
     res = []
     for f in sorted(os.listdir(dirpath)):
         abspath = os.path.join(dirpath, f)
-        if os.path.isdir(abspath):
+        if Path(abspath).is_dir():
             res.extend(findfiles(abspath, match))
 
         if match:
diff --git a/python/grass/script/setup.py b/python/grass/script/setup.py
index c1faaf82b6b..d202cd15582 100644
--- a/python/grass/script/setup.py
+++ b/python/grass/script/setup.py
@@ -148,7 +148,7 @@ def ask_executable(arg):
         ).stdout.strip()
 
     # Directory was provided as a parameter.
-    if path and os.path.isdir(path):
+    if path and Path(path).is_dir():
         return os.fspath(path)
 
     # Executable was provided as parameter.
@@ -156,12 +156,12 @@ def ask_executable(arg):
         # The path was provided by the user and it is an executable
         # (on path or provided with full path), so raise exception on failure.
         path_from_executable = ask_executable(path)
-        if os.path.isdir(path_from_executable):
+        if Path(path_from_executable).is_dir():
             return path_from_executable
 
     # GISBASE is set from the outside or already set.
     env_gisbase = os.environ.get("GISBASE")
-    if env_gisbase and os.path.isdir(env_gisbase):
+    if env_gisbase and Path(env_gisbase).is_dir():
         return env_gisbase
 
     # Executable provided in environment (name is from grass-session).
@@ -170,7 +170,7 @@ def ask_executable(arg):
     grass_bin = os.environ.get("GRASSBIN")
     if grass_bin and shutil.which(grass_bin):
         path_from_executable = ask_executable(grass_bin)
-        if os.path.isdir(path_from_executable):
+        if Path(path_from_executable).is_dir():
             return path_from_executable
 
     # Derive the path from path to this file (Python module).
@@ -191,7 +191,7 @@ def ask_executable(arg):
     grass_bin = "grass"
     if grass_bin and shutil.which(grass_bin):
         path_from_executable = ask_executable(grass_bin)
-        if os.path.isdir(path_from_executable):
+        if Path(path_from_executable).is_dir():
             return path_from_executable
 
     # We fallback to whatever was provided. This may help trace the issue
@@ -227,7 +227,7 @@ def setup_runtime_env(gisbase=None, *, env=None):
 
     runtime_paths = RuntimePaths(env=env, prefix=gisbase)
     gisbase = runtime_paths.gisbase
-    if not os.path.isdir(gisbase):
+    if not Path(gisbase).is_dir():
         gisbase = get_install_path(gisbase)
         # Set the main prefix again.
         # See also the main grass executable code.
diff --git a/python/grass/script/utils.py b/python/grass/script/utils.py
index 232b1286de2..5180356c034 100644
--- a/python/grass/script/utils.py
+++ b/python/grass/script/utils.py
@@ -433,21 +433,22 @@ def alphanum_key(actual_key):
 def get_lib_path(modname, libname=None):
     """Return the path of the libname contained in the module."""
     from os import getenv
-    from os.path import isdir, join, sep
+    from os.path import join, sep
 
-    if isdir(join(getenv("GISBASE"), "etc", modname)):
+    if Path(getenv("GISBASE"), "etc", modname).is_dir():
         path = join(os.getenv("GISBASE"), "etc", modname)
     elif (
         getenv("GRASS_ADDON_BASE")
         and libname
-        and isdir(join(getenv("GRASS_ADDON_BASE"), "etc", modname, libname))
+        and Path(getenv("GRASS_ADDON_BASE"), "etc", modname, libname).is_dir()
     ) or (
         getenv("GRASS_ADDON_BASE")
-        and isdir(join(getenv("GRASS_ADDON_BASE"), "etc", modname))
+        and Path(getenv("GRASS_ADDON_BASE"), "etc", modname).is_dir()
     ):
         path = join(getenv("GRASS_ADDON_BASE"), "etc", modname)
-    elif getenv("GRASS_ADDON_BASE") and isdir(
-        join(getenv("GRASS_ADDON_BASE"), modname, modname)
+    elif (
+        getenv("GRASS_ADDON_BASE")
+        and Path(getenv("GRASS_ADDON_BASE"), modname, modname).is_dir()
     ):
         path = join(os.getenv("GRASS_ADDON_BASE"), modname, modname)
     else:
diff --git a/python/grass/utils/download.py b/python/grass/utils/download.py
index 2e7c1546b0e..670d5403b8e 100644
--- a/python/grass/utils/download.py
+++ b/python/grass/utils/download.py
@@ -127,7 +127,7 @@ def _move_extracted_files(extract_dir, target_dir, files):
     debug("_move_extracted_files({})".format(locals()))
     if len(files) == 1:
         actual_path = os.path.join(extract_dir, files[0])
-        if os.path.isdir(actual_path):
+        if Path(actual_path).is_dir():
             shutil.copytree(actual_path, target_dir)
         else:
             shutil.copy(actual_path, target_dir)
@@ -135,7 +135,7 @@ def _move_extracted_files(extract_dir, target_dir, files):
         Path(target_dir).mkdir(exist_ok=True)
         for file_name in files:
             actual_file = os.path.join(extract_dir, file_name)
-            if os.path.isdir(actual_file):
+            if Path(actual_file).is_dir():
                 # Choice of copy tree function:
                 # shutil.copytree() fails when subdirectory exists.
                 # However, distutils.copy_tree() may fail to create directories before
diff --git a/scripts/g.download.project/g.download.project.py b/scripts/g.download.project/g.download.project.py
index 1f88103301d..27e2b09a660 100644
--- a/scripts/g.download.project/g.download.project.py
+++ b/scripts/g.download.project/g.download.project.py
@@ -70,7 +70,7 @@ def find_location_in_directory(path, recurse=0):
     """
     assert recurse >= 0
     full_paths = [os.path.join(path, i) for i in os.listdir(path)]
-    candidates = sorted([i for i in full_paths if os.path.isdir(i)])
+    candidates = sorted([i for i in full_paths if Path(i).is_dir()])
     for candidate in candidates:
         if is_location_valid(candidate):
             return candidate
diff --git a/scripts/g.extension/g.extension.py b/scripts/g.extension/g.extension.py
index 3d49d5cd2a1..3c5e75c6001 100644
--- a/scripts/g.extension/g.extension.py
+++ b/scripts/g.extension/g.extension.py
@@ -1751,7 +1751,7 @@ def move_extracted_files(extract_dir, target_dir, files):
         Path(target_dir).mkdir(exist_ok=True)
         for file_name in files:
             actual_file = os.path.join(extract_dir, file_name)
-            if os.path.isdir(actual_file):
+            if Path(actual_file).is_dir():
                 # shutil.copytree() replaced by copy_tree() because
                 # shutil's copytree() fails when subdirectory exists
                 copy_tree(actual_file, os.path.join(target_dir, file_name))
@@ -1947,7 +1947,7 @@ def download_source_code(
                 " Please report this to the grass-user mailing list."
             ).format(source)
         )
-    assert os.path.isdir(directory)
+    assert Path(directory).is_dir()
     return directory, url
 
 
@@ -2286,7 +2286,7 @@ def remove_extension_std(name, force=False):
 
     # remove module libraries under GRASS_ADDONS/etc/{name}/*
     libpath = os.path.join(options["prefix"], "etc", name)
-    if os.path.isdir(libpath):
+    if Path(libpath).is_dir():
         gs.verbose(libpath)
         if force:
             shutil.rmtree(libpath)
@@ -2372,7 +2372,7 @@ def create_dir(path):
 
     NOOP for existing directory.
     """
-    if os.path.isdir(path):
+    if Path(path).is_dir():
         return
 
     try:
@@ -2722,7 +2722,7 @@ def resolve_source_code(url=None, name=None, branch=None, fork=False):
         return "official_fork", url
 
     # Handle local URLs
-    if os.path.isdir(url):
+    if Path(url).is_dir():
         return "dir", os.path.abspath(url)
     if Path(url).exists():
         if url.endswith(".zip"):
diff --git a/scripts/v.db.reconnect.all/v.db.reconnect.all.py b/scripts/v.db.reconnect.all/v.db.reconnect.all.py
index eab02276260..55d4d75b1fc 100755
--- a/scripts/v.db.reconnect.all/v.db.reconnect.all.py
+++ b/scripts/v.db.reconnect.all/v.db.reconnect.all.py
@@ -62,7 +62,7 @@
 # substitute variables (gisdbase, location_name, mapset)
 
 
-def substitute_db(database):
+def substitute_db(database) -> str:
     gisenv = gs.gisenv()
     tmpl = string.Template(database)
 
@@ -76,22 +76,22 @@ def substitute_db(database):
 # create database if doesn't exist
 
 
-def create_db(driver, database):
-    subst_database = substitute_db(database)
+def create_db(driver, database) -> bool:
+    subst_database: str = substitute_db(database)
     if driver == "dbf":
-        path = subst_database
+        path = Path(subst_database)
         # check if destination directory exists
-        if not os.path.isdir(path):
+        if not path.is_dir():
             # create dbf database
-            Path(path).mkdir(parents=True)
+            path.mkdir(parents=True)
             return True
         return False
 
     if driver == "sqlite":
-        path = os.path.dirname(subst_database)
+        path = Path(subst_database).parent
         # check if destination directory exists
-        if not os.path.isdir(path):
-            Path(path).mkdir(parents=True)
+        if not path.is_dir():
+            path.mkdir(parents=True)
 
     if (
         subst_database