diff --git a/.github/workflows/deploy.yml b/.github/workflows/deploy.yml
new file mode 100644
index 0000000..be7279c
--- /dev/null
+++ b/.github/workflows/deploy.yml
@@ -0,0 +1,36 @@
+# Deploy branch is followed by Posit Connect
+name: Update Requirements and Manifest on Deploy Branch
+
+on:
+  push:
+    branches:
+      - main  # Trigger when pushing to main
+
+jobs:
+  ci:
+    env:
+      UV_SYSTEM_PYTHON: true
+    runs-on: ubuntu-latest
+
+    steps:    
+      - name: Checkout main
+        uses: actions/checkout@v4
+
+      - name: Setup uv
+        uses: astral-sh/setup-uv@v3
+        with:
+          enable-cache: true
+
+      - name: Generate requirements.txt with `uv`
+        run: uv export --no-hashes -o requirements.txt
+
+      - name: Generate rsconnect-python manifest.json
+        run: uvx --from rsconnect-python rsconnect write-manifest shiny . --entrypoint shinylims.app:app
+
+      - name: Commit changes and push to deploy branch
+        run: |
+          git config --global user.name "github-actions[bot]"
+          git config --global user.email "github-actions[bot]@users.noreply.github.com"
+          git add requirements.txt manifest.json
+          git commit -m "Update requirements on new commit from main" || echo "No changes to commit"
+          git push origin --force HEAD:deploy  # Push to deploy branch, using force because of diverging branches
\ No newline at end of file
diff --git a/manifest.json b/manifest.json
deleted file mode 100644
index 644ec2e..0000000
--- a/manifest.json
+++ /dev/null
@@ -1,57 +0,0 @@
-{
-  "version": 1,
-  "locale": "English_United States.1252",
-  "metadata": {
-    "appmode": "python-shiny",
-    "entrypoint": "shinylims.app:app"
-  },
-  "python": {
-    "version": "3.11.5",
-    "package_manager": {
-      "name": "pip",
-      "version": "24.2",
-      "package_file": "requirements.txt"
-    }
-  },
-  "files": {
-    "requirements.txt": {
-      "checksum": "2976d8cc4dabb78a47c02b90dc75d48e"
-    },
-    ".gitignore": {
-      "checksum": "a490f4da04fb5b1ec743568fe3380d40"
-    },
-    ".python-version": {
-      "checksum": "215923581f8fcce0029639f7ab16ccb6"
-    },
-    "LICENSE": {
-      "checksum": "bbcd65b7e389067d3922f20a2f9eaf4e"
-    },
-    "README.md": {
-      "checksum": "262635faedb2f6c0096957d5b75c6d2c"
-    },
-    "pyproject.toml": {
-      "checksum": "158312210f1c3c22ec358b734eaa34a6"
-    },
-    "src/shinylims/__init__.py": {
-      "checksum": "d41d8cd98f00b204e9800998ecf8427e"
-    },
-    "src/shinylims/app.py": {
-      "checksum": "b561f7e2b81fff588d93ac091dc6a16b"
-    },
-    "src/shinylims/assets/styles.css": {
-      "checksum": "3a235faad5ed32854aa71009d1e7a333"
-    },
-    "src/shinylims/data_utils.py": {
-      "checksum": "91c3c9621a893c9f1163077c8633c8d0"
-    },
-    "src/shinylims/ui_pages.py": {
-      "checksum": "da947ff0de151ce45fc2a3d3f9fe9a81"
-    },
-    "src/shinylims/ui_server.py": {
-      "checksum": "13c704eff839d4b4d8c0e7e801a4b49c"
-    },
-    "uv.lock": {
-      "checksum": "9b96f9b5b26f9ebe3ea91404ecb4ee15"
-    }
-  }
-}
diff --git a/requirements.txt b/requirements.txt
deleted file mode 100644
index b65600a..0000000
--- a/requirements.txt
+++ /dev/null
@@ -1,73 +0,0 @@
-# This file was autogenerated by uv via the following command:
-#    uv export --no-hashes -o requirements.txt
--e .
-anyio==4.6.2.post1
-appdirs==1.4.4
-asgiref==3.8.1
-asttokens==2.4.1
-certifi==2024.8.30
-charset-normalizer==3.4.0
-click==8.1.7 ; platform_system != 'Emscripten'
-colorama==0.4.6 ; sys_platform == 'win32' or platform_system == 'Windows'
-contourpy==1.3.0
-cycler==0.12.1
-decorator==5.1.1
-executing==2.1.0
-faicons==0.2.2
-fonttools==4.54.1
-fsspec==2024.10.0
-h11==0.14.0 ; platform_system != 'Emscripten'
-htmltools==0.5.3
-humanize==4.11.0
-idna==3.10
-importlib-metadata==8.5.0
-importlib-resources==6.4.5
-ipython==8.18.0
-itables==2.0.1
-jedi==0.19.1
-jinja2==3.1.4
-joblib==1.4.2
-kiwisolver==1.4.7
-linkify-it-py==2.0.3
-markdown-it-py==3.0.0
-markupsafe==3.0.2
-matplotlib==3.9.2
-matplotlib-inline==0.1.7
-mdit-py-plugins==0.4.2
-mdurl==0.1.2
-numpy==2.1.2
-packaging==24.1
-pandas==2.2.2
-parso==0.8.4
-pexpect==4.9.0 ; sys_platform != 'win32'
-pillow==11.0.0
-pins==0.8.5
-prompt-toolkit==3.0.36
-ptyprocess==0.7.0 ; sys_platform != 'win32'
-pure-eval==0.2.3
-pygments==2.18.0
-pyparsing==3.2.0
-python-dateutil==2.9.0.post0
-python-multipart==0.0.12
-pytz==2024.2
-pyyaml==6.0.2
-questionary==2.0.1 ; platform_system != 'Emscripten'
-requests==2.32.3
-seaborn==0.13.2
-shiny==0.9.0
-shinyswatch==0.6.1
-six==1.16.0
-sniffio==1.3.1
-stack-data==0.6.3
-starlette==0.41.0
-traitlets==5.14.3
-typing-extensions==4.12.2
-tzdata==2024.2
-uc-micro-py==1.0.3
-urllib3==2.2.3
-uvicorn==0.32.0 ; platform_system != 'Emscripten'
-watchfiles==0.24.0 ; platform_system != 'Emscripten'
-wcwidth==0.2.13
-websockets==13.1
-xxhash==3.5.0
-zipp==3.20.2