diff --git a/tensorrt_llm/_torch/attention_backend/sparse/dsa.py b/tensorrt_llm/_torch/attention_backend/sparse/dsa.py
index 190b3cc85906..266a38f837ab 100644
--- a/tensorrt_llm/_torch/attention_backend/sparse/dsa.py
+++ b/tensorrt_llm/_torch/attention_backend/sparse/dsa.py
@@ -347,6 +347,29 @@ def split_prefill_chunks(
     return chunk_groups
 
 
+# Shrink the indexer prefill chunk size for very long requests to bound the
+# fp8(_fp4)_mqa_logits activation memory (~ chunk_size * K_compressed), keyed on
+# the largest compressed KV length in the batch. Entries are
+# (k_compressed_lower_bound_exclusive, chunk_size); >512K -> 8K, [256K, 512K]
+# -> 16K, otherwise unchanged.
+_INDEXER_CHUNK_SIZE_HEURISTIC = (
+    (512 * 1024, 8 * 1024),
+    (256 * 1024 - 1, 16 * 1024),
+)
+
+
+def select_indexer_chunk_size(configured_chunk_size: int,
+                              max_k_compressed: int) -> int:
+    """Pick the indexer prefill chunk size from the batch's largest K_compressed.
+
+    Only reduces ``configured_chunk_size`` (never increases it).
+    """
+    for threshold, chunk_size in _INDEXER_CHUNK_SIZE_HEURISTIC:
+        if max_k_compressed > threshold:
+            return min(configured_chunk_size, chunk_size)
+    return configured_chunk_size
+
+
 def _select_indexer_compress_ratio(compress_ratios: List[int]) -> int:
     if 4 in compress_ratios:
         return 4
@@ -1778,9 +1801,15 @@ def prepare_for_chunked_prefill(metadata: DSAtrtllmAttentionMetadata,
         else:
             # Use indexer's own chunking logic to prevent L^2 complexity of indexer MQA logits computation for long sequences.
             # This is only used when MLA chunked prefill is not enabled.
+            # Adapt chunk size to the batch's largest K_compressed (see
+            # select_indexer_chunk_size).
+            max_k_compressed = int(indexer_params.kv_lens[:num_contexts].max().
+                                   item()) if num_contexts > 0 else 0
+            effective_chunk_size = select_indexer_chunk_size(
+                metadata.indexer_max_chunk_size, max_k_compressed)
             chunk_groups = split_prefill_chunks(
                 seq_lens[:num_contexts],
-                metadata.indexer_max_chunk_size,
+                effective_chunk_size,
                 start_idx=0,
             )