After written, the disk will be read-only, which means you can use it for any computer you need to boot. This means you only need 1 disk rather than 4 USB drives (leaving only 1 USB required for each quarantined computer. There's also much less opportunity for malware to infect things. There's no possibility for malware to bring data back over from an airgapped machine if the user accidentally re-uses the USB drive or gets them mixed up.