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hg19.json
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hg19.json
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{"references": {
"exomeseq": {
"BWAGENOME": "/fdb/igenomes/Homo_sapiens/NCBI/build37.2/Sequence/BWAIndex/genome.fa",
"CHROMS": ["1","2","3","4","5","6","7","8","9","10","11","12","13","14","15","16","17","18","19","20","21","22","X","Y","MT"],
"GENOME": "/fdb/GATK_resource_bundle/b37/human_g1k_v37.fasta",
"CNVKITGENOME": "/data/CCBR_Pipeliner/db/PipeDB/lib/human_g1k_v37.fasta",
"INDELSITES": "/fdb/GATK_resource_bundle/b37/Mills_and_1000G_gold_standard.indels.b37.vcf",
"NOVOINDEX": "/data/CCBR_Pipeliner/db/PipeDB/lib/human_g1k_v37_iupac.nix",
"REFFLAT": "/data/CCBR_Pipeliner/db/PipeDB/lib/reformatS04380219_qualimap.bed",
"KNOWNANCESTRY": "/data/CCBR_Pipeliner/db/PipeDB/lib/1k_genomes_compSet.vcf -L /data/CCBR_Pipeliner/db/PipeDB/lib/20140520.strict_mask.autosomes.bed",
"SNPSITES": "/fdb/GATK_resource_bundle/b37/dbsnp_138.b37.vcf",
"INDELSITES2": "/fdb/GATK_resource_bundle/b37/1000G_phase1.indels.b37.vcf",
"ALVIEWGENOME": "hg19",
"ANNDIR": "/data/CCBR_Pipeliner/db/PipeDB/AnnovarDB/",
"STRELKA_CONFIG": "/data/CCBR_Pipeliner/db/PipeDB/lib/strelka_demo_config.ini",
"CNVKIT_TARGETS": "/data/CCBR_Pipeliner/db/PipeDB/lib/human_SSv5_cnvkit_targets.bed",
"CNVKIT_ANTITARGETS": "/data/CCBR_Pipeliner/db/PipeDB/lib/human_SSv5_cnvkit_antitargets.bed",
"DELLY_EXCLUSIONS": "/data/CCBR_Pipeliner/db/PipeDB/lib/delly.human.hg19.excl.tsv",
"FASTQ_SCREEN_CONFIG": "/data/CCBR_Pipeliner/db/PipeDB/lib/fastq_screen.conf",
"tg_GS_INDELS": "/fdb/GATK_resource_bundle/hg19-2.8/Mills_and_1000G_gold_standard.indels.hg19.vcf.gz",
"tg_PHASE_INDELS": "/fdb/GATK_resource_bundle/hg19-2.8/1000G_phase1.indels.hg19.vcf.gz",
"SNP138": "/fdb/GATK_resource_bundle/hg19-2.8/dbsnp_138.hg19.vcf.gz",
"HAPMAP": "/fdb/GATK_resource_bundle/hg19-2.8/hapmap_3.3.hg19.vcf.gz",
"B1K": "/fdb/GATK_resource_bundle/hg19-2.8/1000G_phase1.snps.high_confidence.hg19.vcf.gz",
"OMNI": "/fdb/GATK_resource_bundle/hg19-2.8/1000G_omni2.5.hg19.vcf.gz",
"adapter.file": "/data/CCBR_Pipeliner/db/PipeDB/dev/TruSeq_and_nextera_adapters.ngsqc.dat",
"fastqc.adapters": "/data/CCBR_Pipeliner/db/PipeDB/dev/fastqc.adapters",
"trimmomatic.adapters": "/data/CCBR_Pipeliner/db/PipeDB/dev/adapters2.fa",
"ORGANISM": "HUMAN",
"ADAPTER1": "AGATCGGAAGAGCACACGTCTGAACTCCAGTCAC",
"ADAPTER2": "AGATCGGAAGAGCGTCGTGTAGGGAAAGAGTGTAGATCTCGGTGGTCGCCGTATCATT",
"nextera1": "CTGTCTCTTATACACATCTCCGAGCCCACGAGAC",
"nextera2": "CTGTCTCTTATACACATCTGACGCTGCCGACGA",
"gencodeGtf":"gencode.vM4.all.gtf",
"genomeRnaseq": "GRCm38.p3.genome.fa",
"genomeDir": "/data/CCBR_Pipeliner/db/PipeDB/lib/genomes",
"gtfDir": "/data/CCBR_Pipeliner/db/PipeDB/lib/gtf",
"genomeDir2": "/data/CCBR_Pipeliner/db/PipeDB/lib/genomes/2pass",
"gtfERCC": "gencode.vM4.all_ERCC.gtf",
"genomeRnaseqErcc": "GRCm38.p3.ERCC.genome.fa",
"DB29": "/data/CCBR_Pipeliner/db/PipeDB/snpEff_db/dbNSFP2.9.txt.gz",
"SNPEFF_CONFIG": "/usr/local/apps/snpEff/4.2/snpEff.config",
# "FILTERSIFT": "(FILTER='PASS') & ( QUAL >= 20 )", ###maybe change to 30
"FILTERSIFT": "( QUAL >= 20 )",
"SELECTDB": "SIFT_score,SIFT_pred,Polyphen2_HVAR_score,Polyphen2_HVAR_pred,LRT_score,LRT_pred,GERP++_RS,MutationAssessor_score,MutationAssessor_pred,1000Gp1_AF,1000Gp1_EUR_AF,ESP6500_EA_AF,ESP6500_AA_AF",
"SNPEFF_GENOME": "GRCh37.75",
"HAPMAP_DBNSFP": "/data/CCBR_Pipeliner/db/PipeDB/lib/snpEff_db/hapmap.bed",
"REGULOMEDB": "/data/CCBR_Pipeliner/db/PipeDB/lib/snpEff_db/RegulomeDB.bed",
"MUTECTCOSMIC": "/fdb/muTect/cosmic_v67.b37.vcf",
"MUTECTSNP": "/fdb/muTect/dbsnp_137.b37.vcf",
"MUTECTGENOME": "/fdb/muTect/human_g1k_v37.fasta",
"MUTECTVARIANTS": "--dbsnp /fdb/muTect/dbsnp_137.b37.vcf --cosmic /fdb/muTect/cosmic_v67.b37.vcf"
},
"genomeseq": {
"BWAGENOME": "/fdb/igenomes/Homo_sapiens/NCBI/build37.2/Sequence/BWAIndex/genome.fa",
"CHROMS": ["1","2","3","4","5","6","7","8","9","10","11","12","13","14","15","16","17","18","19","20","21","22","X","Y","MT"],
"GENOME": "/fdb/GATK_resource_bundle/b37/human_g1k_v37.fasta",
"CNVKITGENOME": "/data/CCBR_Pipeliner/db/PipeDB/lib/human_g1k_v37.fasta",
"INDELSITES": "/fdb/GATK_resource_bundle/b37/Mills_and_1000G_gold_standard.indels.b37.vcf",
"NOVOINDEX": "/data/CCBR_Pipeliner/db/PipeDB/lib/human_g1k_v37_iupac.nix",
"REFFLAT": "/data/CCBR_Pipeliner/db/PipeDB/lib/reformatS04380219_qualimap.bed",
"KNOWNANCESTRY": "/data/CCBR_Pipeliner/db/PipeDB/lib/1k_genomes_compSet.vcf -L /data/CCBR_Pipeliner/db/PipeDB/lib/20140520.strict_mask.autosomes.bed",
"SNPSITES": "/fdb/GATK_resource_bundle/b37/dbsnp_138.b37.vcf",
"INDELSITES2": "/fdb/GATK_resource_bundle/b37/1000G_phase1.indels.b37.vcf",
"ALVIEWGENOME": "hg19",
"ANNDIR": "/data/CCBR_Pipeliner/db/PipeDB/AnnovarDB/",
"STRELKA_CONFIG": "/data/CCBR_Pipeliner/db/PipeDB/lib/strelka_demo_config.ini",
"CNVKIT_TARGETS": "/data/CCBR_Pipeliner/db/PipeDB/lib/human_SSv5_cnvkit_targets.bed",
"CNVKIT_ANTITARGETS": "/data/CCBR_Pipeliner/db/PipeDB/lib/human_SSv5_cnvkit_antitargets.bed",
"DELLY_EXCLUSIONS": "/data/CCBR_Pipeliner/db/PipeDB/lib/delly.human.hg19.excl.tsv",
"FASTQ_SCREEN_CONFIG": "/data/CCBR_Pipeliner/db/PipeDB/lib/fastq_screen.conf",
"tg_GS_INDELS": "/fdb/GATK_resource_bundle/hg19-2.8/Mills_and_1000G_gold_standard.indels.hg19.vcf.gz",
"tg_PHASE_INDELS": "/fdb/GATK_resource_bundle/hg19-2.8/1000G_phase1.indels.hg19.vcf.gz",
"SNP138": "/fdb/GATK_resource_bundle/hg19-2.8/dbsnp_138.hg19.vcf.gz",
"HAPMAP": "/fdb/GATK_resource_bundle/hg19-2.8/hapmap_3.3.hg19.vcf.gz",
"B1K": "/fdb/GATK_resource_bundle/hg19-2.8/1000G_phase1.snps.high_confidence.hg19.vcf.gz",
"OMNI": "/fdb/GATK_resource_bundle/hg19-2.8/1000G_omni2.5.hg19.vcf.gz",
"adapter.file": "/data/CCBR_Pipeliner/db/PipeDB/dev/TruSeq_and_nextera_adapters.ngsqc.dat",
"fastqc.adapters": "/data/CCBR_Pipeliner/db/PipeDB/dev/fastqc.adapters",
"trimmomatic.adapters": "/data/CCBR_Pipeliner/db/PipeDB/dev/adapters2.fa",
"ORGANISM": "HUMAN",
"ADAPTER1": "AGATCGGAAGAGCACACGTCTGAACTCCAGTCAC",
"ADAPTER2": "AGATCGGAAGAGCGTCGTGTAGGGAAAGAGTGTAGATCTCGGTGGTCGCCGTATCATT",
"nextera1": "CTGTCTCTTATACACATCTCCGAGCCCACGAGAC",
"nextera2": "CTGTCTCTTATACACATCTGACGCTGCCGACGA",
"gencodeGtf":"gencode.vM4.all.gtf",
"genomeRnaseq": "GRCm38.p3.genome.fa",
"genomeDir": "/data/CCBR_Pipeliner/db/PipeDB/lib/genomes",
"gtfDir": "/data/CCBR_Pipeliner/db/PipeDB/lib/gtf",
"genomeDir2": "/data/CCBR_Pipeliner/db/PipeDB/lib/genomes/2pass",
"gtfERCC": "gencode.vM4.all_ERCC.gtf",
"genomeRnaseqErcc": "GRCm38.p3.ERCC.genome.fa",
"DB29": "/data/CCBR_Pipeliner/db/PipeDB/snpEff_db/dbNSFP2.9.txt.gz",
"SNPEFF_CONFIG": "/usr/local/apps/snpEff/4.2/snpEff.config",
# "FILTERSIFT": "(FILTER='PASS') & ( QUAL >= 20 )", ###maybe change to 30
"FILTERSIFT": "( QUAL >= 20 )",
"SELECTDB": "SIFT_score,SIFT_pred,Polyphen2_HVAR_score,Polyphen2_HVAR_pred,LRT_score,LRT_pred,GERP++_RS,MutationAssessor_score,MutationAssessor_pred,1000Gp1_AF,1000Gp1_EUR_AF,ESP6500_EA_AF,ESP6500_AA_AF",
"SNPEFF_GENOME": "GRCh37.75",
"HAPMAP_DBNSFP": "/data/CCBR_Pipeliner/db/PipeDB/lib/snpEff_db/hapmap.bed",
"REGULOMEDB": "/data/CCBR_Pipeliner/db/PipeDB/lib/snpEff_db/RegulomeDB.bed",
"MUTECTCOSMIC": "/fdb/muTect/cosmic_v67.b37.vcf",
"MUTECTSNP": "/fdb/muTect/dbsnp_137.b37.vcf",
"MUTECTGENOME": "/fdb/muTect/human_g1k_v37.fasta",
"MUTECTVARIANTS": "--dbsnp /fdb/muTect/dbsnp_137.b37.vcf --cosmic /fdb/muTect/cosmic_v67.b37.vcf"
},
"rnaseq": {
"GENOMEFILE": "/fdb/GENCODE/Gencode_human/release_19/GRCh37.p13.genome.fa",
"GTFFILE": "/fdb/GENCODE/Gencode_human/release_19/gencode.v19.annotation.gtf",
# "ANNOTATE": "/data/CCBR_Pipeliner/dev/RNA-Seq-pipeline/ver3/Hg19_genes.txt",
"ANNOTATE": "/data/CCBR_Pipeliner/db/PipeDB/dev/Hg19_genes.txt",
"REFFLAT": "/data/CCBR_Pipeliner/db/PipeDB/dev/refFlatHg19.txt",
"RSEMREF": "/data/CCBR_Pipeliner/db/PipeDB/Rnaseq/human_gencode",
"SALMONREF": "/data/CCBR_Pipeliner/db/PipeDB/Rnaseq/human_gencode.transcripts.fa",
# "FASTAWITHADAPTERSETC": "/data/CCBR_Pipeliner/dev/RNA-Seq-pipeline/ver2/TruSeq_and_nextera_adapters_new.fa",
"FASTAWITHADAPTERSETC": "/data/CCBR_Pipeliner/db/PipeDB/dev/TruSeq_and_nextera_adapters_new.fa",
"STARDIR": "/fdb/STAR_2.4.2a/GENCODE/Gencode_human/release_19/genes-",
"RRNALIST": "/data/CCBR_Pipeliner/db/PipeDB/dev/Hg19.rRNA.interval_list_v3"
},
"mirseq": {
"run_info":{
"TOOL": "miRNA",
"VERSION": "1.1",
"PI": "NA",
"FLOWCELL": "external",
"GENOME_BUILD": "hg38",
"MIRBASE_VERSION": "21",
"EMAIL": "[email protected]",
# "SAMPLENAMES": "dA549-KD-a-1_S4_R1_001:dA549-NCTR-a-1_S1_R1_001:dA549-KO-a-2_S5_R1_001:dA549-NCTR-a-2_S3_R1_001:dA549-KD-b-1_S8_R1_001:dA549-NCTR-b-1_S6_R1_001:dA549-KD-b-2_S2_R1_001:dA549-NCTR-b-2-2_S2_R1_001:dH460-KOa-1_S3_R1_001:dH460-NCTR-a-1_S1_R1_001:dH460-KOa-2_S4_R1_001:dH460-NCTR-a-2_S2_R1_001:dH460-KO-b-1_S6_R1_001:dH460-NCTR-b-1_S5_R1_001:dH460-KO-b-2_S8_R1_001:dH460-NCTR-b-2-2_S1_R1_001",
# "LANEINDEX": "-:-:-:-",
"TRIM_ADAPTER": "YES",
"CALL_SNVS": "YES",
"DIFF_EXPRESSION": "YES",
"DIFF_EXPRESSION_ANALYSES": "mir_knockdown",
# "INPUT_DIR": "/",
# "OUTPUT_DIR": "out",
"TOOL_INFO": "tool_info",
"SAMPLE_INFO": "sample_info",
# "DELIVERY_FOLDER": "/scratch/dwheeler/test5/out",
# "USE_SGE": "0",
# "USE_PORTAL": "0",
# "PORTAL_PROJECT_NAME": "NA"
},
"reference_files": {
"BOWTIE_REF": "/data/CCBR_Pipeliner/db/PipeDB/miRseq/References/genome",
"GENCODE_GTF": "/fdb/GENCODE/GRCh38/21/GTF/gencode.v21.annotation.gtf",
"MIRBASE_GFF": "/data/CCBR_Pipeliner/db/PipeDB/miRseq/References/hsa.gff3",
"MIRBASE_HAIRPIN": "/data/CCBR_Pipeliner/db/PipeDB/miRseq/References/hairpin.fa",
"MIRBASE_MATURE": "/data/CCBR_Pipeliner/db/PipeDB/miRseq/References/mature.fa",
# For miRspring which uses its own set of files
"MIRBASE_FILES": "/data/CCBR_Pipeliner/db/PipeDB/miRseq/References",
# "MIRBASE_GFF": "/data/dwheeler/miRspring/miRbase_Files/hsa.gff2",
# "MIRBASE_HAIRPIN": "/data/dwheeler/miRspring/miRbase_Files/hsa.nt35.fa",
# "MIRBASE_MATURE": "/data/dwheeler/miRspring/miRbase_Files/mature.fa",
# "MIRBASE_FILES": "/data/dwheeler/miRspring/miRbase_Files/",
"REF_GENOME": "/data/CCBR_Pipeliner/db/PipeDB/miRseq/References/genome.fa",
"REF_GENOME_IUPAC": "/data/CCBR_Pipeliner/db/PipeDB/miRseq/References/genome-iupac.fa",
"TARGET_DATA": "/data/CCBR_Pipeliner/db/PipeDB/miRseq/References",
},
},
"chipseq":{},
}
}