diff --git a/.bumpversion.cfg b/.bumpversion.cfg
index b3305bbc71..e5849499b7 100644
--- a/.bumpversion.cfg
+++ b/.bumpversion.cfg
@@ -1,5 +1,5 @@
 [bumpversion]
-current_version = 65.0.16
+current_version = 66.0.0
 commit = True
 tag = True
 tag_name = v{new_version}
diff --git a/cg/__init__.py b/cg/__init__.py
index b1be0757db..ff31930010 100644
--- a/cg/__init__.py
+++ b/cg/__init__.py
@@ -1,2 +1,2 @@
 __title__ = "cg"
-__version__ = "65.0.16"
+__version__ = "66.0.0"
diff --git a/pyproject.toml b/pyproject.toml
index 0b182bbdfd..fdc59b1fe2 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -4,7 +4,7 @@ build-backend = "poetry.core.masonry.api"
 
 [project]
 name = "cg"
-version = "65.0.16"
+version = "66.0.0"
 description = "Clinical Genomics command center"
 readme = {file = "README.md", content-type = "text/markdown"}
 homepage = "https://github.com/Clinical-Genomics/cg"