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egfr_classes

Repository containing the scripts for the analyses in the manuscript Decoding the Clinical and Molecular Signatures of EGFR Common, Compound, and Uncommon Mutations in Non-Small Cell Lung Cancer

All the steps are performed following EGFRclasses_pipeline.R. The clinical and molecular data for the various datasets was retreived from the sources cited in the manuscript.

EGFRclasses_MutationListConstruction_step1.R, EGFRclasses_MutationListConstruction_step2.R: Construction of the list of EGFR mutations, assignment to the classes, filtering.

EGFRclasses_Preprocessing.R: Collection and harmonization of clinical data, assignment to EGFR classes.

EGFRclasses_functions.R: Functions implementing each analysis.

EGFRclasses_pipeline.R: Pipeline calling the analysis functions.

EGFRclasses_utils.R: Generic helper functions for plotting.