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Convert Omics Solution to Cobra Model #48

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Rohak72 opened this issue Jul 8, 2024 · 0 comments
Open

Convert Omics Solution to Cobra Model #48

Rohak72 opened this issue Jul 8, 2024 · 0 comments

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@Rohak72
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Rohak72 commented Jul 8, 2024

Hello @vmspereira,

Thanks for creating this tool! I have been able to generate GIMME and E-Flux solutions on my transcriptomic data, but was wondering if there was a way to convert these objects into a useable cobra model that retains the flux values + objective provided in the solution. I've tried to copy the original model, add in the solution-defined constraints, and remove reactions with zero flux, but the objective repeatedly remains unchanged. Additionally, in the case of E-Flux, when I execute the protocol above, I'm left with a model of objective 0.0, with all reactions having zero flux.

If you have any feedback regarding this, please let me know. Thanks again!

Best,
Rohak

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