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Thanks for creating this tool! I have been able to generate GIMME and E-Flux solutions on my transcriptomic data, but was wondering if there was a way to convert these objects into a useable cobra model that retains the flux values + objective provided in the solution. I've tried to copy the original model, add in the solution-defined constraints, and remove reactions with zero flux, but the objective repeatedly remains unchanged. Additionally, in the case of E-Flux, when I execute the protocol above, I'm left with a model of objective 0.0, with all reactions having zero flux.
If you have any feedback regarding this, please let me know. Thanks again!
Best,
Rohak
The text was updated successfully, but these errors were encountered:
Hello @vmspereira,
Thanks for creating this tool! I have been able to generate GIMME and E-Flux solutions on my transcriptomic data, but was wondering if there was a way to convert these objects into a useable cobra model that retains the flux values + objective provided in the solution. I've tried to copy the original model, add in the solution-defined constraints, and remove reactions with zero flux, but the objective repeatedly remains unchanged. Additionally, in the case of E-Flux, when I execute the protocol above, I'm left with a model of objective 0.0, with all reactions having zero flux.
If you have any feedback regarding this, please let me know. Thanks again!
Best,
Rohak
The text was updated successfully, but these errors were encountered: