diff --git a/samtools/1.10/Dockerfile b/samtools/1.10/Dockerfile
new file mode 100644
index 000000000..9d2e05fa7
--- /dev/null
+++ b/samtools/1.10/Dockerfile
@@ -0,0 +1,52 @@
+  
+################## BASE IMAGE ######################
+
+FROM biocontainers/biocontainers:v1.1.0_cv2
+
+################## METADATA ######################
+
+ARG software_version=1.7.0
+LABEL base_image="biocontainers:v1.1.0_cv2"
+LABEL software="samtools"
+LABEL version="1.10"
+LABEL software.version="$software_version"
+LABEL about.summary="Tools for manipulating next-generation sequencing data"
+LABEL about.home="https://github.com/samtools/samtools"
+LABEL about.documentation="https://github.com/samtools/samtools"
+LABEL about.license_file="https://github.com/samtools/samtools"
+LABEL about.license_file="https://github.com/samtools/samtools/blob/develop/LICENSE"
+LABEL about.license="SPDX:MIT"
+LABEL about.tags="Genomics"
+LABEL extra.identifiers.biotools="SAMTOOLS"
+LABEL extra.binaries="samtools"
+
+################## MAINTAINER ######################
+MAINTAINER Alvin Chen <ychen@aperiomics.com>
+
+ENV ZIP=samtools-1.10.tar.bz2
+ENV URL=https://sourceforge.net/projects/samtools/files/samtools/1.10
+ENV FOLDER=samtools-1.10
+ENV DST=/home/biodocker/bin
+ENV ULOCAL=/usr/local/bin
+
+USER 0
+
+RUN apt-get update
+RUN apt-get install -y libz-dev libncurses5-dev libncursesw5-dev libbz2-dev liblzma-dev libcurl4-openssl-dev
+RUN wget $URL/$ZIP/download -O $DST/$ZIP && \
+    cd $DST && \ 
+    tar -jvxf $ZIP && \
+    rm $ZIP && \
+    cd $FOLDER/ && \
+    make && \
+    cd /data/ && \
+    mv $DST/$FOLDER/* $DST && \
+    rmdir $DST/$FOLDER
+
+RUN ln -s $DST/* $ULOCAL/
+
+USER biodocker
+
+WORKDIR /data/
+
+# CMD ["samtools"]