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<!doctype html>
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<h1 class="full-width text-center small-spacer">BigBrain Warp</h1>
<div class="text-box">BigBrain is a singular dataset that offers an ultra-high-resolution (20µm) volumetric reconstruction of a sliced and stained post-mortem human brain (Amunts et al. 2013). BigBrainWarp aims to enable integration of BigBrain with neuroimaging and other neurobiological modalities, helping a wide range of neuroscientists to utilise the cytoarchitectural information encoded in BigBrain for multi-scale neuroscientific discovery.</div>
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<div class="tool-name">Visiting Scholar: Andrija Štajduhar</div>
<div class="tool-maker"><em>date: Jan 16 2025</em></div>
<div class="tool-description">Written synopsis by Andrija Stajduhar
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<div class="tool-name">Featured Scholar: Blake Richards</div>
<div class="tool-maker"><em>date:</em> May 5 2022</div>
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Video interview with Blake Richards
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<div class="tool-name">Featured Scholar: Jordan DeKraker</div>
<div class="tool-maker"><em>date:</em> Jan 12 2022</div>
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Video interview with Jordan DeKraker
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<a href="https://youtu.be/sheS62GV5o8" class="tool-link">go to youtube <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-name">Featured Scholar: Sofie Valk</div>
<div class="tool-maker"><em>date:</em> Nov 15 2021</div>
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Video interview with Sofie Valk
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<div class="tool-name">Featured Scholar: Konrad Wagstyl</div>
<div class="tool-maker"><em>date:</em> June 22 2021</div>
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Video interview with Konrad Wagstyl
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<a href="https://youtu.be/ez7u4e9ZBq0" class="tool-link">go to youtube <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-name">Featured: voluba</div>
<div class="tool-maker"><em>date: June 1 2023</em></div>
<div class="tool-description">A common problem in high-resolution brain atlasing is spatial anchoring of volumes of interest from imaging experiments into the anatomical context of an ultrahigh-resolution reference model like BigBrain.
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<div class="tool-name">New website launched presenting the Julich Brain Atlas</div>
<div class="tool-maker"><em>date: July 11 2022</em></div>
<div class="tool-description">The new Julich Brain Atlas website has been launched in July 2022 presenting the concept and research behind the human brain atlas developed by teams at the Institute of Neuroscience Medicine (INM-1) at Forschungszentrum Jülich and the Cécile and Oscar Vogt Institute for Brain Research in Düsseldorf.
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<div class="tool-name">Featured: Neuromaps</div>
<div class="tool-maker"><em>date: July 28 2022</em></div>
<div class="tool-description">Neuromaps – structural and functional interpretation of brain maps.
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<a href="featured-project-neuromaps.html" class="tool-link">go to the project <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-name">Featured: A multi-scale model of neurotransmitter receptor alterations in Alzheimer’s disease progression</div>
<div class="tool-maker"><em>date: April 7 2022</em></div>
<div class="tool-description">A project presented by Ahmed Khan (lab of Yasser Iturria-Medina)
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<a href="https://youtu.be/PixOjq590Aw" class="tool-link">go to youtube <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-name">Featured: Cytoarchitectonic Maps of the Human Metathalamus in 3D space</div>
<div class="tool-maker"><em>date: Feb 14 2022</em></div>
<div class="tool-description">Two new maps in the BigBrain available, medial geniculate body and lateral geniculate body by Kai Kiwitz and Andrea Brandstetter
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<a href="https://www.youtube.com/watch?v=TpKwpD1G0kw" class="tool-link">go to youtube <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-name">Featured: Siibra</div>
<div class="tool-maker"><em>date: Dec 01 2021</em></div>
<div class="tool-description">Our featured project the siibra toolsuite.
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<div class="tool-name">Featured: BigBrain Warp</div>
<div class="tool-maker"><em>date: Apr 01 2021</em></div>
<div class="tool-description">Our featured tool developed by Casey Paquola and Boris Bernhardt.
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<a href="https://bigbrainwarp.readthedocs.io/en/latest/" class="tool-link">go to the project <i class="fas fa-arrow-right"></i></a><br>
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<div class="tool-name">Featured Paper: Integrating brainstem and cortical functional architectures</div>
<div class="tool-maker"><em>date: Jan 31, 2025</em></div>
<div class="tool-description">In this study (“Integrating brainstem and cortical functional architectures”), we sought out to understand the functional interplay between the cortex and brainstem in awake humans.
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<div class="tool-name">Featured: Self-supervised representation learning for nerve fiber distribution patterns in 3D-PLI</div>
<div class="tool-maker"><em>date: Nov 26, 2024</em></div>
<div class="tool-description">Quantifiable and interpretable descriptors of nerve fiber architecture at microscopic resolution provide an important foundation for a deeper understanding of human brain architecture.
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<div class="tool-name">Featured: Laminar Thickness Profiles</div>
<div class="tool-maker"><em>date: Aug 21, 2023</em></div>
<div class="tool-description">We recently published a study on the variation of cortical laminar structure in the BigBrain dataset. The cerebral cortex consists of six cortical layers which are horizontally superimposed stripes of gray matter with characteristic features such as size, type and density of the neurons.
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<div class="tool-name">Architecture and connectivity of the human angular gyrus and of its homolog region in the macaque brain</div>
<div class="tool-maker"><em>date: April 2023</em></div>
<div class="tool-description">The angular gyrus (AG) is a horseshoe-shaped region of the posterior inferior parietal lobe in the human brain. It has attracted major interest since it’s a higher-order associative cortical region that plays a prominent role in the integration of multiple sensory systems.
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<div class="tool-name">Primate cerebellar scaling in connection to the cerebrum: a 34-species phylogenetic comparative analysis</div>
<div class="tool-maker"><em>date: Mar 2023</em></div>
<div class="tool-description">The cerebellum has long been viewed as a functionally homogenous structure, only involved in the fine control of the motor system. However, over the last decades it has become increasingly clear that the cerebellum contributes to wide-ranging higher-order associative function, such as abstract reasoning, theory of mind, and affect regulation, as well.
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<div class="tool-name">CLOSING THE MECHANISTIC GAP: THE VALUE OF MICROARCHITECTURE IN UNDERSTANDING COGNITIVE NETWORKS</div>
<div class="tool-maker"><em>date: Aug 2022</em></div>
<div class="tool-description">Contemporary research linking spatial patterns of neural activity to psychological constructs describes “where” hypothesised functions occur, but not “how” these regions contribute to cognition.
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<div class="tool-name">Convolutional Neural Networks for cytoarchitectonic brain mapping at large scale</div>
<div class="tool-maker"><em>date: Sept 2022</em></div>
<div class="tool-description">A novel method for automatic classification of cytoarchitectonic brain areas in large series of consecutive histological brain sections.
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<div class="tool-name">Cellular structure of the human metathalamus revealed in novel 3D map</div>
<div class="tool-maker"><em>date: April 2022</em></div>
<div class="tool-description">A new, high-resolution 3D map of a previously unmapped area of the brain has been reconstructed by a team of HIBALL researchers as part of the Human Brain Project (HBP).
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<div class="tool-name">Julich-Brain</div>
<div class="tool-maker"><em>date: Sept 2021</em></div>
<div class="tool-description">Julich-Brain – a 3D probabilistic atlas of human brain’s cytoarchitecture
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